2018年7月8日日曜日

Alcohol and health


Small amount of sake is considered “medicine”

How many glasses of this Chatan craft beer are good for health?


Sake, alcoholic drink made from rice, produces a special “appetite” for food, especially in the autumn. At dinner, Japanese usually increase their appetite when sake is served. Good combination of alcohol drink is beer and edamame (green pea); wine and meat dish; awamori (Okinawa rice alcohol) and champloo (mixed fried vegetables) are served in a small plate with small quantity of food. This makes drinkers in good shape (weight). Recently in Japan, the popularity of craft beer is rising. Sango (coral) beer or Chatan beer are popular in Okinawa, and Nest beer is in Ibaraki Prefecture, located northeast of Tokyo.

Sake is believed to be the source of hundred medicines. Red wine, on the other hand, is regarded as a source of health for people around the Mediterranean countries such as France. In addition to antioxidant contained in wine called polyphenols, wine is said to have another substance called resveratrol. Its function may inhibit or slow aging. However, the effect of resveratrol has not yet been confirmed in clinical trials.

A lot of liquor consumption is considered poison to the body

Drinking too much is not recommended. It is medically and socially prohibited specially among the minors. Long-term heavy drinking destroys liver, pancreas, brain, and nerves. There are many diseases associated with alcohol intake: cirrhosis of liver, chronic pancreatitis, cerebral atrophy, neuropathy and other diseases. There is a risk of carcinogenesis (cancer-forming) in long-term alcohol drinkers. These cancer by locations are found in the colon, female breast, mouth, pharynx, larynx, liver, esophagus, stomach, pancreas, lung, and gallbladder. All are cancer related to alcohol consumption.

Also, binge drinking on a single day is dangerous. Acute alcoholism may result in aspiration pneumonia, which may lead to respiratory arrest due to suppression of respiratory centers. It is dangerous to drink a lot at university clubs and parties to welcome new members that involves dangerous alcohol. We strongly suggest to the students to stop this harmful tradition. Although drunk driving is self-destructive, there is also a risk of killing others, so it is social menace.

Even if you are not driving, there is a risk of traumatic death such as injuries due to falls and injuries due to falling from train station, going back home hit in the railroad track, or fighting with other customs with heavy drinking. In Japan, there are still many people who smoke while drinking. If you drink alcohol often with people who smoke, it is an exposure to secondhand smoke.

Estimated amount of health drinking

So how much do you drink alcohol? First, there is no need to forcibly make a person drink if he cannot or do not drink. Originally, people who do not have enzyme called acetaldehyde (toxic by-product of alcohol) cannot drink alcohol basically. Also, Oriental people whose face is flushed red with a little alcohol intake are known to be at high risk of esophageal cancer.

As a measure of alcohol consumption, the standard estimate based on the amount of pure alcohol (ethanol) ingested is used. Using this amount of ethanol (grams), it is recommended to use standard unit of 1 drink in each country, 10 grams = 1 drink in Japan. Australia and New Zealand also use the same grams as Japan, but in America 14 grams = 1 drink.

In traditional guidelines, it was recommended that up to 1 drink per day for women and 1 to 2 drinks for men. One drink is 250 mL for beer or Happo Shu (a kind of beer) (5%), 180 mL for Chu-Hai (sake mixed with soda) (7%), 50 mL for Shochu (sake made from potato or wheat) (25%), 80 mL (0.5 cups) for Japanese sake (15%), Whiskey, or Gin etc. (40%), or 30 mL for wine (12%).

Healthy drinking amount different for men and women

Previous epidemiological studies on alcohol consumption and disease showed a J-shaped curve. In other words, light drinking is better than zero drinking amount, but the health outcomes are good, but if it is more than the amount of indicated above, the risk of drinking, risk of drinking will be higher, and higher than those with zero drinking.

In addition to heart diseases such as heart failure, cerebrovascular disorders, diabetes, etc., the risk of total mortality is also J-shaped. However, the important thing when evaluating alcohol consumption and health risks is the effect of smoking. Drinking people have higher rate of smoking than non-drinkers, and it is difficult to evaluate epidemiological results, as risk of cancer increases considerably due to smoking.

Recently, research in the United States focusing on the risk of "cancer" was announced. The results showed that in non-smoking men, the risk of cancer does not increase in the case of mild drinking up to 2 drinks a day. Women, on the other hand, show that even if mild drinking up to 1 drink a day, the risk of breast cancer increases. As an advice based on this latest result, women with a family history of breast cancer are at high risk of breast cancer, so we recommend that those women better refrain from drinking alcohol.

References

Cao Y, Willett WC, Rimm EB, Stampfer MJ, Giovannucci EL. Light to moderate intake of alcohol, drinking patterns, and risk of cancer: results from two prospective US cohort studies. BMJ. 2015 Aug 18; 351: h4238:
https://www.bmj.com/content/351/bmj.h4238


2018年7月1日日曜日

Do not smoke cigarettes

My uncle and tobacco


Tobacco is the number one enemy of public health in Okinawa.

I often hear the question "Why did you enter medical school and became a doctor?” Let me just answer this question with a narrative. When I was in the first grade in elementary school, I felt like I wanted to be a doctor. At the age of 6, I suffered from acute rheumatic fever, and had an inflammation of the heart, and valvular disease. When I visited a clinic, the doctor told me: "I can hear noises (murmurs) from the heart, but I cannot see them".

During this critical time, we received a message from my cousin who has been working in Kyoto and asked me to come to hospital in Kyoto. Right away, my father and I decided to go to Kyoto. We visited a hospital in Kyoto and met with the doctor for the first time. The doctor did follow the standard procedure like my chief complaint, history of the present illness, physical examination and auscultation using stethoscope, etc. When everything has been examined, the doctor finally made his diagnosis and ready to reveal his findings. My father and I anxiously waited for that few seconds. And suddenly we heard powerful words from my doctor: “this is no big deal anymore”.

That was the biggest assurance the doctor gave us about my present health condition. Upon hearing the doctor, my father immediate got relieved from uncertainty of my health condition. Because of this remarkable impression the doctor gave me as a first-grade elementary school student, I thought "a doctor was amazing". At that time, I started gradually longing and hoping to become a doctor in the future.

After few years, I entered junior high school and decided to consult with my uncle (the father of my cousin who asked me several years ago to go to Kyoto hospital) about entrance exam to medical school. My uncle was active in the community and was a chairperson of local education. His advice was very helpful for my future medical entrance examination. With hard work in school and great advice, (thanks to my uncle) I was able to pass successfully the entrance examination and admitted to medical school.

Aside from being an active person in the community, my uncle enjoyed tobacco/cigarette (smoking) since he was young. Through many years of smoking, my uncle, who gave me a guidance in preparing for entrance exam in medicine, developed emphysema (chronic obstructive pulmonary disease) due to smoking. It was a sad news to the entire family members and relatives.

For the meantime, I graduated from medical school and became a doctor. During my clinical practice at a hospital in Okinawa, my uncle was hospitalized with acute exacerbation of emphysema of the lungs. Due to complication of emphysema, he died in the hospital. I got so frustrated and felt so sad and sorry for my uncle. He could have lived a longer and healthier life if he did not smoke. My father also smoked during that period. He stopped smoking when he saw my uncle’s condition and finally died in the hospital due to smoking.

Smoking and its consequences in the world 

The smoking rate in Japan and European countries has declined over the past 60 years. On the other hand, the sad reality is that smoking rates are rising in 40 countries. Tobacco smoking has been recognized for many years without doubt: it causes sickness and death by the millions of people in the world. Smoking is the single biggest cause of death. And yet the prevalence of cigarette smoking has not decreased dramatically. Why?

The first factor is that the government actions are still insufficient in preventing smoking. Educating the general public and smokers intensively and extensively about the toxicity of smoking is not effective. Raising cigarette taxes; no smoking in public places; and supporting the people who would like to quit smoking are proven effective.

Although WHO recommends cigarette tax of 3/4 (75%) of the retail price or more, the tax rate of tobacco in Japan is about 65%, but it is still relatively higher compared to low tax rate among developed countries, resulting in low tobacco prices.

The Review Committee of the Ministry of Health, Labor and Welfare reports that "It is important to lower smoking rate (no. of smokers) by raising the tobacco price and tobacco tax now; and that we need to continue making efforts to realize that."

The second factor is the pressure from the tobacco company. The American movie entitled: "Insider" (directed by Michael Mann, and starring Al Pacino and Russell Crowe, shown in 1999) depicting anti-social pressure and misleading campaign by tobacco company was a real story. For example, cigarette companies do business by misrepresentation and deceit. The companies usually use brand strategy such as "light", "slim",’ "mint", but the harm to health is the same.

The third factor is the difficulty to change the behavior of smokers. In addition to public education, promotion of smoking cessation among the outpatient is important. Understanding that smoking is a disease called nicotine addiction is a prerequisite. All smokers must recognize that addiction is a disease. In public places, it is important to introduce a complete non-smoking rule.

Most domestic airports, cafes and restaurants have introduced smoking designated areas in Japan. Non-smoking rule is more important to introduce in public places like in Western countries.

In conclusion, it is a top priority to support smoking cessation, due to the extremely high morbidity and mortality caused by tobacco. More than 6 million people in the world die each year; and it is estimated that 8 million people in the world population will die every year by 2030, unless the smoking rate remains as it is. Many of the mortality would come from people in developing countries. The world needs to unite and create a movement that could focus on smoking cessation. China with its biggest number of smokers (1/3) of the population started a powerful non-smoking campaign.

My own proposal is to ban smoking in all public places. Government bureaucrats in the world must also start non-smoking rule during work, inside and outside their buildings. Smoking ban could prevent millions of sickness and save millions of lives.

By the way, the first-grade elementary school boy was Dr Yasuharu Tokuda.